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Ms Stratton, who took on the role of Downing Street Press Secretary last November, is now in quarantine, Express.co.uk understands.
It is not clear if Ms Stratton has tested positive or came into contact with someone who has.
The former Newsnight journalist was employed by Number 10 to front White House like briefings.
But her debut has been delayed several times due to the pandemic.
Her briefings were due to begin in October with a former courtroom in Downing Street converted into a hi-tech studio setting.
That start date was pushed back to January 11 but was then put on hold again.
Health Secretary Matt Hancock went into self-isolation earlier this week after coming into close contact with someone who has tested positive for coronavirus.
He said he was alerted by the NHS app on Monday evening, having led a Downing Street press conference.
Mr Hancock must quarantine despite having tested positive for Covid-19 in March, announcing his diagnosis shortly after Mr Johnson revealed his own.
It is understood that the Health Secretary was given the duration of his isolation period by the NHS app.
The health service’s website says the isolation period includes the day the individual was last in contact with the person who tested positive and the next 10 full days.
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