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Motorists face delays of around one hour as the northbound carriageway is shut between junction 17 for Sandbach, Cheshire, and Holmes Chapel in the same county. There are currently five miles of traffic with queues almost reaching junction 16 for Crewe and Barthomley.
According to the traffic monitoring service Inrix a lorry has veered off the road and gone up the grass verge.
Six fire engines are at the scene, Manchester Evening News reports.
North West Motorway Police tweeted: “Due to a police incident, the M6 between J18 and J18 northbound will be closed for some time please find alternative routes.”
And Highways England said: “This incident is causing delays of over 60 minutes above the normal travel time and five miles of congestion almost back to J16 near Barthomley.”
Traffic is congested southbound from around junction 19 at Northwich, Cheshire, as onlookers slow when going past the accident.
Diversions are in place northbound and will be for the rest of the day.
They’re advised to leave at junction 16 and use the A500 and A34 through Talke, Staffordshire, to Congleton.
Drivers can then take the A54 northwest to rejoin the M6 at junction 18 – but motorists are warned these dual-carriageways are also congested as a result.
There are also unrelated problems on the railways in the same region, adding to travel delays.
A vehicle hit a bridge between Wilmslow and Crewe and so there are delays on Avanti West Coast services between Manchester Piccadilly and London Euston, Northern services between Liverpool Lime Street / Manchester Piccadilly and Crewe andTransport for Wales services between Manchester Piccadilly and Cardiff Central / Carmarthen / Milford Haven.
A statement on National Rail Enquiries’ website reads: “A road vehicle colliding with a bridge between Wilmslow and Crewe is causing disruption to journeys between these stations.
“Services may be cancelled, delayed by up to 30 minutes or diverted via Stoke-on-Trent.
“We anticipate disruption will continue until 11am.”
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