Pre-market Movers: ARDX, GRTX, BBWI, PXMD, TNYA …

Takeda: Phase 3 PhALLCON Trial Meets Primary Endpoint

Takeda (TAK) announced that the phase 3 PhALLCON trial met its primary endpoint, showing that adult patients with newly-diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia treated with ICLUSIG plus reduced-intensity chemotherapy achieved higher rates of minimal residual disease-negative complete remission compared to imatinib. In the trial, no new safety signals were observed. The PhALLCON study is a phase 3 randomized, international, open-label multicenter trial.

Takeda said the data from this trial will be discussed with regulatory agencies and shared with the scientific community in the future.

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iPhone’s price markup remains way below inflation rate

The price of the base model of the iPhone increased 25 per cent between 2017 and 2022, whereas inflation rose 29.7 per cent between September 2017 and September 2022.

At Rs 79,900 for the base model (iPhone 14), Apple’s iPhone is more expensive than most other smartphones.

Still, a Business Standard analysis found that Apple iPhones have not even beaten inflation over the past six years.

The price of the base model of the iPhone increased 25 per cent between 2017 and 2022, whereas inflation rose 29.7 per cent between September 2017 and September 2022.

The Pro model, however, has been way higher than consumer inflation. Between 2017 to 2022, the prices of the iPhone Pro model went up 46 per cent.

The Cupertino giant’s base model tablet (iPad) has witnessed a 55.4 per cent price increase over the past six years.

Recently, Apple’s base-level iPad was made available in India for Rs 44,900. Although Apple has made significant design changes to the tablet, the price received a considerable bump of Rs 14,000 over last year.

Feature Presentation: Ashish Narsale/

Pound tumbles against dollar after Hunt’s budget sparks market fears

Jeremy Hunt announces changes to measures from mini-budget

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Following Jeremy Hunt’s statement in the House of Commons, sterling dropped more than 1.2 percent to 1.177 dollars.

The currency was 0.5 percent lower at 1.14 euros.

FTSE 100 Index was also 0.7 percent lower at 7301.8.

Mike Owens, Senior Sales Trader at Saxo UK, said that while the pound rebounded in the early weeks of Rishi Sunak’s administration, the budget “nevertheless paints a bleak picture of the state of the UK economy”.


Colorado snow totals for Nov. 17, 2022

The following Colorado snow totals have been reported by the National Weather Service for Nov. 17, 2022, as of 11:30 a.m. Thursday:

Boulder, CO — 1.3 inches at 12:03 p.m. CST

Denver Intl Airpo, CO — 0.3 inch at 12:02 p.m. CST

Genesee, CO — 2.8 inches at 12:02 p.m. CST

Greeley, CO — 1.1 inches at 12:39 p.m. CST

Parker, CO — 1.5 inches at 11:21 a.m. CST

Treasury Reveals Details Of Two-Year, Five-Year & Seven-Year Note Auctions

The Treasury Department on Thursday announced the details of this month’s auctions of two-year, five-year and seven-year notes.

The Treasury revealed plans to sell $42 billion worth of two-year notes, $43 billion worth of five-year notes and $35 billion worth of seven-year notes.

The results of both the two-year and five-year note auctions will be announced next Monday, while the results of the seven-year note auction will be announced next Tuesday.

Last month, the Treasury also sold $42 billion worth of two-year notes, $43 billion worth of five-year notes and $35 billion worth of seven-year notes.

The two-year note auction attracted average demand, the five-year note auction attracted above average demand and the seven-year note auction attracted modestly below average demand.

Denver metro area after-school closures for Nov. 17, 2022

On days with severe weather, school closures and government office closures will be updated throughout the day.

A status of “Other” means there is an early closing or some cancellations — check the website by clicking the name in the list.

Perfect Gains 19%

Shares of Perfect Corp. (PERF) are gaining more than 19 percent on Thursday morning trade. There were no corporate announcements today to influence the stock movement. The shares have been trending up since November 14 after the company revealed the benefits of AI skin technology for the dermatology and medical spa industries.

Currently, shares are at $10.69, up 19.71 percent from the previous close of $8.93 on a volume of 266,736.

Pre-market Movers: ARDX, GRTX, BBWI, PXMD, TNYA …

The following are some of the stocks making big moves in Thursday’s pre-market trading (as of 06.40 A.M. ET).

In the Green

Ardelyx, Inc. (ARDX) is up over 77% at $2.16
Galera Therapeutics, Inc. (GRTX) is up over 25% at $2.19
Bath & Body Works, Inc. (BBWI) is up over 21% at $37.69
PaxMedica, Inc. (PXMD) is up over 21% at $2.08
Golden Sun Education Group Limited (GSUN) is up over 13% at $4.89
Cartesian Growth Corporation (GLBL) is up over 10% at $9.55
Youdao, Inc. (DAO) is up over 6% at $4.12

In the Red

Tenaya Therapeutics, Inc. (TNYA) is down over 20% at $2.55
OncoSec Medical Incorporated (ONCS) is down over 19% at $3.17
SenesTech, Inc. (SNES) is down over 16% at $2.73
Bionomics Limited (BNOX) is down over 13% at $7.38
Global-e Online Ltd. (GLBE) is down over 11% at $21.80
Tian Ruixiang Holdings Ltd (TIRX) is down over 9% at $2.70
Ormat Technologies, Inc. (ORA) is down over 8% at $91.24
Perfect Corp. (PERF) is down over 7% at $8.25
Silvergate Capital Corporation (SI) is down over 6% at $29.28
Borr Drilling Limited (BORR) is down over 6% at $4.78
Quad/Graphics, Inc. (QUAD) is down over 6% at $3.116